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| The Virtual Galleries | Cape Town | Visual Communications, Photography, Design | |
| SIQNAL (Pty) Ltd | Bloemfontein | Web Development | |
| The Bold Circle App Developers | Johannesburg | Mobile App Development, Performance Marketing | |
| Yellow Lizard Creative Strategic Marketing | Port Elizabeth | Advertising / Marketing / Design / Online Marketin | |
| Unlimited Badges and Signs | Pretoria | Button Badges and Vehicle branding | |
| Zania Group | Bloemfontein | Business Development Solutions | |
| Studio FU | Knysna | Design, Production & Laser Cutting | |
| Slabbert Custom Furniture | Cape Town | Manufacturer, Retail, Marketing and Sales | |
| Web Savvy Marketing | Johannesburg | Web Design Johannesburg | |
| Tracy Gander | South Africa | Digital strategy | |
| Thumbtribe | Ballito | Measurable engagement in store & online | |
| Surge Digital | Cape Town | Digital Marketing | |
| Web Smart | Johannesburg | Digital Marketing | Google AdWords | |
| Terabyte Website Design Pietermarizburg | Pietermaritzburg | Website Design and Online Marketing | |
| Web Assist | Durban | Website Design and Website Hosting | |
| Wilson Web Design and SEO | Cape Town | Web Design/SEO/Hosting | |
| Tone Media | Cape Town | Digital Printing, Graphic Design & Web Development | |
| Weblab | Durban | Web Design, Website Design, Online Marketing, SEO | |
| Web SEO | Cape Town | SEO Company and Web Development | |
| Silverline Print | Vanderbijlpark | Label design & print | |
| Simon Barnett Web Design and Development | Cape Town | Front End Web Development, Web Design | |
| Simpaul Design | Nairobi | Brand Identity | |
| Simple Moose Design Studio | Randburg | Internet Marketing | |
| Simplr Creative | Cape Town | Branding/UI & UX design | |
| Singlebond | CENTURION | Web Design and Domain Hosting | |
| Sirdotcom Technology | Durban | System development and Web applications | |
| SitePRO | Cape Town | Webdesign & Development | |
| SitesDeveloper | Randburg | Website design and development | |
| Sittings Restaurant and Bar | Mafikeng | Events, catering, accommodation, and creative desi | |
| Six Fingaz Media | Johannesburg | South African Ad Agency based in Johannesburg. | |
| SJ Artists | Cape Town | Artist and project management agency. | |
| SJ Webdesign Studio | Cape Town | Complete Website Design & Development | |
| Skytouch Media | Cape Town | Online Marketing | |
| Sliced Cheese Designs | Durban | Sliced Cheese Designs | |
| SL Studios | Pretoria | Graphic Design | |
| Smart Digital Media | Paarl | Web Design, Hosting, Print, Graphic design | |
| Smart Events | Roodepoort | Event Management Consultancy | |
| Smart SEO | Durban | SEO | Website Design Umhlanga | |
| SMARTSIGNS | Johannesburg | Signage Manufcturer: Design-Manufacture-Install | |
| Smit & Van Wyk | Pretoria | Patents, Trademarks, Copyright | |
| SNWS Digital | Brakpan | Web design , Graphic design, logo design, | |
| Social Distancing Stickers | Cape Town | Marketing, Printing, eCommerce, Social Distancing | |
| Solo Graphica | Cape Town | Graphic Design | |
| Somerset West Web Design and Development | Cape Town | Web Development | |
| Somethingraphic | Graphic Design | ||
| Sonar Studios | Cape Town | Music Composition, ADR, Final Mix, Sound Design | |
| Sondlo & Knopp Advertising | East London | Advertising (TTL) | |
| SoPro Branding & Signs | Amanzimtoti | Signage, Printing, Branding & Websites | |
| Sorted Design + Advertising | Pretoria | Graphic Design, Advertising, Web Design, Branding | |
| Soulfilter | Roodepoort | Video editing design motion graphics animation VFX | |
| Sound Surgeon Studios | Cape Town | Score, Recording, Sound Design, Foley, Mixing | |
| South Coast Directory | South Coast | Internet Marketing Directory | |
| South Florida Lead SEO | Hollywood | Internet Marketing Web Design SEO Leads | |
| Sovtech SA | Johannesburg | Software Developement Company | |
| Spearhead | Video, design and content production | ||
| Spika | South Africa | Design & illustration | |
| Spinaxis Creative | Edenvale | Graphic Design, Photography, Website Development | |
| Spiraleye Studios | Highveld Techno Park | Software Multimedia, web, consulting, marketing | |
| Spitfire | Johannesburg | Branding | |
| SP Supplies | Cape Town | Print, Design, Branding, Office Supplies | |
| Squiggle | Johannesburg | At Squiggle we believe in individuality, in giv... | |
| SSQ Exhibitions | Johannesburg | Exhibition Stands, PermaneInteriors, Mall Displays | |
| Stained Design | Johannesburg | Design in general - from A to Z | |
| Star Boi Entertainment | Pretoria | Photography/Graphic Design | |
| Star Leo Advertising | Kampala | Media buying, strategy, creative, PR, social media | |
| Staroot Media | Vosloorus | Media Communication | |
| startupAFRICA Media (Pty) Ltd | Johannesburg | Marketing, Radio & TV advertising, Media Planning | |
| Stealth Services | Johannesburg | Web Development | |
| Stellar Radio Networks | Cape Town | Retail Radio Broadcast and Instore Audio Services | |
| Stephanie Photography | Cape Town | Cape Town Photographer | |
| Stoneworks Signage & Print cc | Cape Town | 3D Printing, Graphic Design, Digital Printing | |
| Storyteller SEO | Cape Town | Search Engine Optimisation | |
| Stractiv8 | Johannesburg | Communications & Digital Engagement | |
| Straight Twisted Advertising | Advertising & Marketing Communications. | ||
| Stratcom Branding | Johannesburg | On and offline Brand Architecture | |
| Strategic Online Marketing Services | Sandton | Digital Marketing | |
| Strategy Brand Imagineers | Port Elizabeth | Digital, Design, Brand Strategy | |
| Stratsmith Marketing Solutions | Midrand | Brand strategy and communications | |
| Structural Mezzanine Floors | Cape Town | Structural Mezzanine Floors, manufacture & install | |
| Studio112 | Pretoria | Below the line (advertising) | |
| Studio26 Design & Branding | Parys | Web design, graphic design, sign design & DTP | |
| Studio 5 | Johannesburg | Graphic Design Web Design Online and Digital Rep | |
| Studio Dolby | Stellenbosch | Graphic Design | |
| Studio Franco | Cape Town | Freelance all graphic design services | |
| Studio Franco Design | South Africa. | Design and Marketing | |
| STARC | Cape Town | Residential and Commercial building design | |
| Stunning Creations | Pretoria | Shopfitting | |
| SugarBird Creative Design | Logo's, weddings, kids parties, adverts, labels | ||
| Sumi Creative | Co | Artist, Designer, Furniture | ||
| Sum of 21 Academy | Creative Academy and Incubator | ||
| Superb Digital | Website design/development | ||
| Supernice | Web and mobile apps | ||
| Superseed Studio | Cape Town | Digital marketing, Brand Design, Web Development | |
| Supreme Shopfitters | Johannesburg | Manufacture/Installers of Shopfittings/Furn. | |
| Svn Events Management and Marketing | Johannesburg | Events planning and marketing | |
| SwanCircle | Cape Town | User Experience Design | |
| Swell Communications | Pretoria | Public Relations | |
| Swey Design | Stellenbosch | Communications, PR, Graphic Design, Publishing |
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